Recombinant CD45RA 抗体 (full length)
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北京 101111
Quick Overview for Recombinant CD45RA 抗体 (full length) (ABIN7877903)
抗原
See all CD45RA 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- CD45RA Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human PTPRC protein was used as the immunogen for the CD45RA antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the CD45RA antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the CD45RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD45RA
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别名
- CD45RA
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背景
- CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
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UniProt
- P08575
抗原
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