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Recombinant CA8 抗体 (full length)

The 小鼠 单克隆 anti-CA8 antibody (Clone rCA8-8835) (ABIN7877776) specifically detects CA8 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7877776
发货至: 中国
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Quick Overview for Recombinant CA8 抗体 (full length) (ABIN7877776)

抗原

See all CA8 抗体
CA8 (Carbonic Anhydrase VIII (CA8))

抗体类型

Recombinant Antibody

适用

  • 69
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宿主

  • 43
  • 26
小鼠

克隆类型

  • 40
  • 29
单克隆

标记

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  • 1
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This CA8 antibody is un-conjugated

应用范围

  • 40
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Western Blotting (WB)

质量等级

Carrier-free

克隆位点

RCA8-8835
  • 抗原表位

    • 15
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    full length

    原理

    CA8 Antibody / Carbonic Anhydrase VIII (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human protein was used as the immunogen for the CA8 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the CA8 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the CA8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CA8 (Carbonic Anhydrase VIII (CA8))

    别名

    CA8

    背景

    The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.

    UniProt

    P35219
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