Recombinant CA8 抗体 (full length)
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Quick Overview for Recombinant CA8 抗体 (full length) (ABIN7877774)
抗原
See all CA8 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Carbonic Anhydrase VIII Antibody / CA8 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human protein was used as the immunogen for the Carbonic Anhydrase VIII antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the Carbonic Anhydrase VIII antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Carbonic Anhydrase VIII antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CA8 (Carbonic Anhydrase VIII (CA8))
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别名
- Carbonic Anhydrase VIII
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背景
- The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.
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UniProt
- P35219
抗原
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