CREB5 抗体 (full length)
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北京 101111
Quick Overview for CREB5 抗体 (full length) (ABIN7877764)
抗原
See all CREB5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- CREB5 Antibody / CRE-BPa
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human CREB5 protein was used as the immunogen for the CREB5 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the CREB5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CREB5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))
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别名
- CREB5
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背景
- The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.
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UniProt
- Q02930
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途径
- Thyroid Hormone Synthesis
抗原
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