Recombinant Caldesmon 抗体 (full length)
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Quick Overview for Recombinant Caldesmon 抗体 (full length) (ABIN7877756)
抗原
See all Caldesmon (CALD1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- Recombinant CALD1 Antibody/ Caldesmon / CAD (HMW)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human full-length CALD1 protein was used as the immunogen for the recombinant CALD1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the recombinant CALD1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant CALD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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别名
- CALD1
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背景
- Recognizes a protein of 150 kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
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UniProt
- Q05682
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途径
- Myometrial Relaxation and Contraction
抗原
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