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Recombinant Caldesmon 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects Caldesmon in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7877756
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Recombinant Caldesmon 抗体 (full length) (ABIN7877756)

抗原

See all Caldesmon (CALD1) 抗体
Caldesmon (CALD1) (Caldesmon 1 (CALD1))

抗体类型

Recombinant Antibody

适用

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宿主

  • 132
  • 33
小鼠

克隆类型

  • 98
  • 67
单克隆

标记

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This Caldesmon antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RCALD1-7266
  • 抗原表位

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    full length

    原理

    Recombinant CALD1 Antibody/ Caldesmon / CAD (HMW)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant human full-length CALD1 protein was used as the immunogen for the recombinant CALD1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the recombinant CALD1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant CALD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Caldesmon (CALD1) (Caldesmon 1 (CALD1))

    别名

    CALD1

    背景

    Recognizes a protein of 150 kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.

    UniProt

    Q05682

    途径

    Myometrial Relaxation and Contraction
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