Calcineurin B 抗体 (full length)
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北京 101111
Quick Overview for Calcineurin B 抗体 (full length) (ABIN7877753)
抗原
See all Calcineurin B (CAN) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Calcineurin B Antibody / PPP3R1 (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant full-length human Calcineurin B protein was used as the immunogen for the Calcineurin B antibody.
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亚型
- IgG2a, kappa
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anti-Calcineurin B (CAN) (AA 1-170) antibody
CAN 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcineurin B (CAN) (AA 3-29), (N-Term) antibodyCAN 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22165 unconjugated
anti-Calcineurin B (CAN) (AA 1-110) antibodyCAN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D9 unconjugated
anti-Calcineurin B (CAN) (AA 1-173) antibodyCAN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcineurin B (CAN) (N-Term) antibodyCAN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcineurin B (CAN) (AA 9-38), (N-Term) antibodyCAN 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Calcineurin B (CAN) (AA 1-173) antibodyCAN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Calcineurin B (CAN) (AA 1-173) antibodyCAN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Calcineurin B antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Calcineurin B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Calcineurin B (CAN)
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别名
- Calcineurin B
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背景
- Calcineurin is an enzyme that dephosphorylates serine and threonine residues in proteins. It is a heterodimer of a 59 kDa catalytic A subunit and a 19 kDa regulatory B subunit that is activated by the binding of calcium ions and calmodulin. Calcineurin is expressed in many tissues, but its levels are highest in the brain, where it may play a role in learning and memory. It has many substrates, including NFAT, a transcription factor that is activated by dephosphorylation. Complexes of the immuno-suppressants cyclosporine and FK506 with immunophilin proteins such as cyclophilin and FKBP12 are potent and specific inhibitors of Calcineurin activity. Alterations in Calcineurin activity are suspected to play a role in cardiac hypertrophy and graft versus host disease in organ transplantation.
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UniProt
- P63098
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途径
- Cellular Glucan Metabolic Process, VEGF Signaling
抗原
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