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BCL11A 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects BCL11A in ELISA, IF 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7877690
发货至: 中国
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for BCL11A 抗体 (full length) (ABIN7877690)

抗原

See all BCL11A 抗体
BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This BCL11A antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-BCL11A-1H3
  • 抗原表位

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    full length

    原理

    B-cell lymphoma/leukemia 11A Antibody / BCL11A (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human protein was used as the immunogen for the B-cell lymphoma/leukemia 11A antibody.

    亚型

    IgG1
  • 应用备注

    Optimal dilution of the B-cell lymphoma/leukemia 11A antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the B-cell lymphoma/leukemia 11A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

    别名

    B-cell lymphoma/leukemia 11A

    背景

    Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

    UniProt

    Q9H165

    途径

    Regulation of Cell Size
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