Annexin a1 抗体 (full length)
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北京 101111
Quick Overview for Annexin a1 抗体 (full length) (ABIN7877678)
抗原
See all Annexin a1 (ANXA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- Annexin A1 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant human full-length protein was used as the immunogen for the Annexin A1 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Annexin A1 antibody to be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Annexin A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- Annexin A1
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背景
- The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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