Recombinant YWHAE 抗体 (full length)
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北京 101111
Quick Overview for Recombinant YWHAE 抗体 (full length) (ABIN7877575)
抗原
See all YWHAE 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- Recombinant 14-3-3E Antibody / YWHAE
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human full-length protein was used as the immunogen for the recombinant 14-3-3E antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the recombinant 14-3-3E antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant 14-3-3E antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- YWHAE (14-3-3 epsilon (YWHAE))
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别名
- 14-3-3E
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背景
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.
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UniProt
- P62258
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途径
- Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
抗原
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