SOD2 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for SOD2 抗体 (C-Term) (ABIN7877480)
抗原
See all SOD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- C-Term
-
原理
- Superoxide Dismutase 2 Antibody / SOD2
-
序列
- QYKNVRPDYL KAIWNVINWE NVTERYMACK K
-
纯化方法
- Antigen affinity purified
-
免疫原
- C-terminal amino acids QYKNVRPDYLKAIWNVINWENVTERYMACKK were used as the immunogen for the Superoxide Dismutase 2 antibody.
-
亚型
- IgG2b
-
-
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 25-222) antibody
SOD2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibodySOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) antibodySOD2 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8H3D2 unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) antibodySOD2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 8H3F9 unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 192-222), (C-Term) antibodySOD2 适用: 人, 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 41-78) antibodySOD2 适用: 人, 小鼠, Pig, 绵羊 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody (PE)SOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal PE
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody (Atto 390)SOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody (Atto 488)SOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody (FITC)SOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal FITC
-
-
应用备注
- Optimal dilution of the Superoxide Dismutase 2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Superoxide Dismutase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
-
别名
- Superoxide Dismutase 2
-
背景
- SOD2 (Superoxide Dismutase 2), also called IPO-B or MNSOD, is a mitochondrial matrix enzyme that scavenges oxygen radicals produced by the extensive oxidation-reduction and electron transport reactions occurring in mitochondria. This gene is a member of the iron/manganese superoxide dismutase family. Using a somatic cell hybrid panel containing different segments of chromosome 6, they demonstrated that SOD2 is located in the region 6q25.3-qter which, together with the FISH analysis, indicated that SOD2 is in the distal portion of 6q25. The SOD2 gene encodes an intramitochondrial free radical scavenging enzyme that is the first line of defense against superoxide produced as a byproduct of oxidative phosphorylation. Adeno-associated viral delivery of the human SOD2 gene resulted in suppression of optic nerve degeneration and rescue of retinal ganglion cells. The findings suggested that reactive oxygen species contributed to retinal cell death and optic nerve damage in mice with complex I deficiency, and that expression of SOD2 attenuated the disease process.
-
UniProt
- P04179
-
途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
抗原
-
