Paired Box 3 抗体 (C-Term)
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Quick Overview for Paired Box 3 抗体 (C-Term) (ABIN7877443)
抗原
See all Paired Box 3 (PAX3) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- C-Term
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原理
- PAX3 Antibody / Paired box 3 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A synthetic peptide from the C-terminus region of the quail protein was used as the immunogen for the PAX3 antibody.
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亚型
- IgG2a, kappa
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应用备注
- Optimal dilution of the PAX3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the PAX3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Paired Box 3 (PAX3)
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别名
- PAX3
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背景
- Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.
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UniProt
- P23760
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途径
- Sensory Perception of Sound, Tube Formation
抗原
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