POR 抗体 (C-Term)
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北京 101111
Quick Overview for POR 抗体 (C-Term) (ABIN7877442)
抗原
See all POR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Cytochrome P450 Reductase Antibody / POR / CYPOR
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序列
- RNMARDVQNT FYDIVAELGA MEHAQAVDYI KKLMTK
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纯化方法
- Antigen affinity purified
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免疫原
- C-terminal region amino acids RNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTK from the human protein were used as the immunogen for the Cytochrome P450 Reductase antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the Cytochrome P450 Reductase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Cytochrome P450 Reductase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- POR (P450 (Cytochrome) Oxidoreductase (POR))
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别名
- Cytochrome P450 Reductase
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背景
- POR is a membrane-bound enzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of the eukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
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UniProt
- P16435
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
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