Acetyl-CoA Carboxylase beta 抗体 (C-Term)
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Quick Overview for Acetyl-CoA Carboxylase beta 抗体 (C-Term) (ABIN7877306)
抗原
See all Acetyl-CoA Carboxylase beta (ACACB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- ACACB Antibody / Acetyl-CoA carboxylase 2
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纯化方法
- Antigen affinity
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免疫原
- A peptide from the C-terminal region of human Acetyl-CoA carboxylase 2 protein was used as the immunogen for this ACACB antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ACACB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ACACB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Acetyl-CoA Carboxylase beta (ACACB)
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别名
- ACACB
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背景
- Acetyl-CoA carboxylase 2 also known as ACC-beta or ACC2 is an enzyme that in humans is encoded by the ACACB gene. It is mapped to 12q24.11. Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.
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UniProt
- O00763
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途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process
抗原
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