Recombinant alpha Tubulin 抗体 (acLys40)
Our Local Distributor
北京 101111
Quick Overview for Recombinant alpha Tubulin 抗体 (acLys40) (ABIN7877304)
抗原
See all alpha Tubulin (TUBA1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- acLys40
-
原理
- Alpha Tubulin (acetyl K40) Antibody / TUBA1B/TUBA4A
-
纯化方法
- Affinity-chromatography
-
免疫原
- A synthesized peptide derived from human alpha Tubulin (acetyl K40) was used as the immunogen for the Alpha Tubulin (acetyl K40) antibody.
-
亚型
- IgG
-
-
anti-alpha Tubulin (TUBA1) antibody
TUBA1 适用: 人, 小鼠, Pig, Saccharomyces cerevisiae, Arabidopsis, Nicotiana tabacum, Paramecium, Eisenia fetida, Turkey WB, IHC (p), ICC, IP, ICFC 宿主: 小鼠 Monoclonal TU-01 unconjugated
anti-alpha Tubulin (TUBA1) antibody (FITC)TUBA1 适用: 人, 小鼠, Pig, Saccharomyces cerevisiae, Arabidopsis, Nicotiana tabacum, Paramecium, Eisenia fetida, Turkey ICC, FACS 宿主: 小鼠 Monoclonal TU-01 FITC
anti-alpha Tubulin (TUBA1) antibody (Biotin)TUBA1 适用: 人, 小鼠, Pig, Saccharomyces cerevisiae, Arabidopsis, Nicotiana tabacum, Paramecium, Eisenia fetida, Turkey WB, IHC (p), ICC, ICFC 宿主: 小鼠 Monoclonal TU-01 Biotin
anti-alpha Tubulin (TUBA1) antibodyTUBA1 适用: 人, 小鼠, 大鼠, Pig, Nicotiana tabacum, 犬 WB, ELISA, IHC (p), ICC, IP 宿主: 小鼠 Monoclonal TU-16 unconjugated
anti-alpha Tubulin (TUBA1) (acLys40) antibodyTUBA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-alpha Tubulin (TUBA1) (AA 380-460) antibodyTUBA1 适用: 人, 小鼠, 大鼠, 小鸡 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha Tubulin (TUBA1) (acLys40) antibodyTUBA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha Tubulin (TUBA1) antibodyTUBA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha Tubulin (TUBA1) antibodyTUBA1 适用: 人, 小鼠, 大鼠, Pig, Cow, Saccharomyces cerevisiae, 猴, 犬, Hamster, 豚鼠, Amphibian, Sea Urchin, 山羊, Kangaroo WB, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal DM1A unconjugated
anti-alpha Tubulin (TUBA1) (Subunit alpha) antibodyTUBA1 适用: 人, Saccharomyces cerevisiae, 哺乳动物, Avian, Drosophila melanogaster, Fungus WB, IHC, ELISA, IHC (p), IHC (fro), RIA 宿主: 大鼠 Monoclonal YOL1-34 unconjugated
-
-
应用备注
- Optimal dilution of the Alpha Tubulin (acetyl K40) antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store the Alpha Tubulin (acetyl K40) antibody at -20oC.
-
-
- alpha Tubulin (TUBA1)
-
别名
- Alpha Tubulin
-
背景
-
Alpha Tubulin (acetyl K40) antibody detects alpha tubulin specifically when acetylated at lysine 40. Alpha tubulin, encoded by multiple genes including TUBA1A, TUBA3C, and TUBA4A, is one of the two principal subunits of microtubules, the dynamic cytoskeletal polymers critical for cell shape, intracellular transport, and mitotic spindle formation. Common alternate identifiers include TUBA1 and TUBA4, which are widely referenced in literature. Acetylation of lysine 40 is a well known post translational modification associated with stable, long lived microtubules that support transport and signaling.
Alpha Tubulin (acetyl K40) antibody is widely applied in cell biology, neurobiology, and cancer research. Microtubule acetylation is enriched in neuronal axons, cilia, and stable cytoskeletal structures. By detecting acetylation at lysine 40, researchers can evaluate how microtubules achieve stability and how post translational modifications regulate cytoskeletal dynamics.
Immunofluorescence with Alpha Tubulin (acetyl K40) antibody highlights stable microtubule tracks in neurons and ciliated cells. Immunohistochemistry maps tissue regions enriched in acetylated tubulin, while western blotting detects the modified isoform as distinct from total tubulin. These assays provide powerful tools for studying cytoskeletal regulation.
Acetylation at lysine 40 is mediated by alpha tubulin acetyltransferase (ATAT1) and reversed by histone deacetylase 6. Dysregulation of this balance contributes to neurodegenerative disease, cancer, and ciliopathies. By applying this phospho specific antibody, scientists can examine mechanisms of axonal transport, sensory signaling, and tumor progression.
Alpha Tubulin (acetyl K40) antibody from NSJ Bioreagents provides strong specificity for detecting this critical post translational modification. Its performance supports both basic and translational studies of microtubule biology. -
UniProt
- P68363
-
途径
- Microtubule Dynamics
抗原
-
