NECAB3 抗体 (AA 97-339)
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Quick Overview for NECAB3 抗体 (AA 97-339) (ABIN7877271)
抗原
See all NECAB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 97-339
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原理
- NECAB3 Antibody / N-terminal EF-hand calcium-binding protein 3
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids D97-D339) was used as the immunogen for the NECAB3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NECAB3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NECAB3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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别名
- NECAB3
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背景
- N-terminal EF-hand calcium-binding protein 3 is a protein that in humans is encoded by the NECAB3 gene. The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q96P71
抗原
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