MTAP 抗体 (AA 97-196)
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北京 101111
Quick Overview for MTAP 抗体 (AA 97-196) (ABIN7877264)
抗原
See all MTAP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 97-196
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原理
- MTAP Antibody / S-methyl-5'-thioadenosine phosphorylase
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 97-196 from the human protein was used as the immunogen for the MTAP antibody.
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亚型
- IgG2b, kappa
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anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-154) antibody
MTAP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G4 unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 1-283) antibodyMTAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) antibodyMTAP 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) antibodyMTAP 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 97-196) antibodyMTAP 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal MTAP-1813 unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 97-196) antibodyMTAP 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, Hamster WB, IHC, ELISA 宿主: 兔 Monoclonal MTAP-3137R unconjugated Recombinant Antibody
anti-Methylthioadenosine phosphorylase (MTAP) (Internal Region) antibodyMTAP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methylthioadenosine phosphorylase (MTAP) (AA 97-196) antibodyMTAP 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal rMTAP-1813 unconjugated Recombinant Antibody
anti-Methylthioadenosine phosphorylase (MTAP) antibodyKD Validated MTAP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4560 unconjugated Recombinant Antibody
anti-Methylthioadenosine phosphorylase (MTAP) (AA 8-37), (N-Term) antibodyMTAP 适用: 人 WB 宿主: 兔 Polyclonal RB42759 unconjugated
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应用备注
- Optimal dilution of the MTAP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the MTAP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MTAP (Methylthioadenosine phosphorylase (MTAP))
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别名
- MTAP
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背景
- Recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.
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UniProt
- Q13126
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途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
抗原
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