ITGA3 抗体 (AA 96-324)
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Quick Overview for ITGA3 抗体 (AA 96-324) (ABIN7877250)
抗原
See all ITGA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 96-324
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原理
- Integrin alpha 3 Antibody / ITGA3
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids L96-L324) was used as the immunogen for the Integrin alpha 3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Integrin alpha 3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Integrin alpha 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ITGA3 (Integrin, alpha 3 (ITGA3))
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别名
- Integrin alpha 3
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背景
- ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. It is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. This gene is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the ?3?1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.
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UniProt
- P26006
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途径
- CXCR4-mediated Signaling Events, Integrin Complex
抗原
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