PIAS1 抗体 (AA 96-300)
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Quick Overview for PIAS1 抗体 (AA 96-300) (ABIN7877248)
抗原
See all PIAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 96-300
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原理
- PIAS1 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids Q96-K300) was used as the immunogen for the PIAS1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PIAS1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PIAS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
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别名
- PIAS1
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背景
- E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene. It is mapped to 15q23. This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.
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UniProt
- O75925
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途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
抗原
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