SYCP1 抗体 (AA 95-717)
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北京 101111
Quick Overview for SYCP1 抗体 (AA 95-717) (ABIN7877226)
抗原
See all SYCP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 95-717
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原理
- SYCP1 Antibody / Synaptonemal complex protein 1
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纯化方法
- Immunogen affinity purified
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免疫原
- E.coli-derived human SYCP1 recombinant protein (Position: D95-H717) was used as the immunogen for the SYCP1 antibody.
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亚型
- IgG
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anti-Synaptonemal Complex Protein 1 (SYCP1) antibody
SYCP1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 1 (SYCP1) (C-Term) antibodySYCP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 1 (SYCP1) (AA 72-121) antibodySYCP1 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 1 (SYCP1) (AA 51-150) antibodySYCP1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 1 (SYCP1) (N-Term) antibodySYCP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 1 (SYCP1) antibodySYCP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 1 (SYCP1) (C-Term) antibodySYCP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 1 (SYCP1) (AA 927-955), (C-Term) antibodySYCP1 适用: 人 WB 宿主: 兔 Polyclonal RB37284 unconjugated
anti-Synaptonemal Complex Protein 1 (SYCP1) (N-Term) antibodySYCP1 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptonemal Complex Protein 1 (SYCP1) (C-Term) antibodySYCP1 适用: 小鼠, 大鼠 IHC (p), IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SYCP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SYCP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SYCP1 (Synaptonemal Complex Protein 1 (SYCP1))
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别名
- SYCP1
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背景
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SYCP1 antibody detects Synaptonemal complex protein 1, encoded by the SYCP1 gene. Synaptonemal complex protein 1 is a structural protein that forms the transverse filaments of the synaptonemal complex during meiosis. SYCP1 antibody provides researchers with a specific reagent for studying meiotic chromosome pairing, synapsis, and fertility.
Synaptonemal complex protein 1 plays a fundamental role in meiotic prophase I. Research using SYCP1 antibody has shown that it bridges homologous chromosomes by connecting lateral elements composed of SYCP2 and SYCP3. This zipper-like structure stabilizes pairing and promotes homologous recombination, ensuring proper segregation of chromosomes. Without SYCP1, homologous pairing fails, leading to meiotic arrest and infertility.
Studies with SYCP1 antibody have revealed that disruption of synaptonemal complex protein 1 causes sterility in both male and female model organisms. In humans, variants in SYCP1 have been linked to cases of infertility, demonstrating its conserved role in reproductive biology. Its structural role makes SYCP1 a key marker for meiotic progression.
Beyond meiosis, SYCP1 has been used as a biomarker for germ cell development. Research using SYCP1 antibody has shown that its expression is restricted to meiotic cells, allowing it to be used as a reliable marker for spermatogenesis and oogenesis studies. This makes SYCP1 antibody a valuable tool for developmental and reproductive biology research.
SYCP1 antibody is widely applied in immunohistochemistry, immunofluorescence, and western blotting. Immunohistochemistry highlights expression in testis and ovary, immunofluorescence demonstrates localization along meiotic chromosomes, and western blotting quantifies expression during gametogenesis. These applications make SYCP1 antibody indispensable for meiosis research.
By providing validated SYCP1 antibody reagents, NSJ Bioreagents supports studies into meiotic recombination, synaptonemal complex assembly, and infertility. Detection of Synaptonemal complex protein 1 provides researchers with insight into how meiotic structures safeguard chromosome segregation. -
UniProt
- Q15431
抗原
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