PIAS2 抗体 (AA 93-311)
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Quick Overview for PIAS2 抗体 (AA 93-311) (ABIN7877179)
抗原
See all PIAS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 93-311
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原理
- PIAS2 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids E93-K311) was used as the immunogen for the PIAS2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PIAS2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PIAS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PIAS2 (Protein Inhibitor of Activated STAT, 2 (PIAS2))
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别名
- PIAS2
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背景
- E3 SUMO-protein ligase PIAS2 is an enzyme that in humans is encoded by the PIAS2 gene. It is mapped to 18q21.1. This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.
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UniProt
- O75928
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途径
- JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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