Claudin 7 抗体 (AA 92-211)
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北京 101111
Quick Overview for Claudin 7 抗体 (AA 92-211) (ABIN7877154)
抗原
See all Claudin 7 (CLDN7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 92-211
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原理
- Claudin 7 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant partial protein (amino acids F92-V211) was used as the immunogen for the Claudin 7 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Claudin 7 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Claudin 7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Claudin 7 (CLDN7)
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别名
- Claudin 7
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背景
- Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.
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UniProt
- O95471
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途径
- Hepatitis C
抗原
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