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Bestrophin 1 抗体 (AA 9-551)

This 兔 多克隆 antibody specifically detects Bestrophin 1 in WB 和 ELISA. It exhibits reactivity toward 小鼠 和 大鼠.
产品编号 ABIN7877093
发货至: 中国
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Quick Overview for Bestrophin 1 抗体 (AA 9-551) (ABIN7877093)

抗原

See all Bestrophin 1 (BEST1) 抗体
Bestrophin 1 (BEST1)

适用

  • 24
  • 5
  • 4
  • 2
  • 2
  • 1
小鼠, 大鼠

宿主

  • 22
  • 4

克隆类型

  • 24
  • 2
多克隆

标记

  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Bestrophin 1 antibody is un-conjugated

应用范围

  • 19
  • 8
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 9-551

    原理

    Best1 Antibody / Bestrophin 1

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived mouse recombinant protein (amino acids V9-E551) was used as the immunogen for the Best1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Best1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Best1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Bestrophin 1 (BEST1)

    别名

    Best1

    背景

    Bestrophin-1 (Best1) is a protein that in humans is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

    UniProt

    O88870
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