Bestrophin 1 抗体 (AA 9-551)
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Quick Overview for Bestrophin 1 抗体 (AA 9-551) (ABIN7877093)
抗原
See all Bestrophin 1 (BEST1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-551
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原理
- Best1 Antibody / Bestrophin 1
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived mouse recombinant protein (amino acids V9-E551) was used as the immunogen for the Best1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Best1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Best1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Bestrophin 1 (BEST1)
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别名
- Best1
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背景
- Bestrophin-1 (Best1) is a protein that in humans is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
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UniProt
- O88870
抗原
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