SERPINC1 抗体 (AA 89-464)
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Quick Overview for SERPINC1 抗体 (AA 89-464) (ABIN7877059)
抗原
See all SERPINC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 89-464
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原理
- SERPINC1 Antibody / Antithrombin III
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R89-K464) was used as the immunogen for the SERPINC1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SERPINC1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SERPINC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
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别名
- SERPINC1
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背景
- Serpin peptidase inhibitor, clade C (antithrombin), member 1, also known as Antithrombin III (AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
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UniProt
- P01008
抗原
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