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MBNL1 抗体 (AA 89-388)

This 兔 多克隆 antibody specifically detects MBNL1 in WB, ELISA, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7877057
发货至: 中国
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Quick Overview for MBNL1 抗体 (AA 89-388) (ABIN7877057)

抗原

See all MBNL1 抗体
MBNL1 (Muscleblind-like Protein 1 (MBNL1))

适用

  • 39
  • 5
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 猴

宿主

  • 32
  • 6
  • 1

克隆类型

  • 30
  • 9
多克隆

标记

  • 27
  • 4
  • 3
  • 3
  • 1
  • 1
This MBNL1 antibody is un-conjugated

应用范围

  • 35
  • 22
  • 8
  • 7
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 89-388

    原理

    Muscleblind-like 1 Antibody / MBNL1

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids Q89-M388) was used as the immunogen for the Muscleblind-like 1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Muscleblind-like 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Muscleblind-like 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    MBNL1 (Muscleblind-like Protein 1 (MBNL1))

    别名

    Muscleblind-like 1

    背景

    Muscleblind-like (Drosophila), also known as MBNL1, is a protein that in humans is encoded by the MBNL1 gene. It is mapped to 3q25.1-q25.2. This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.

    UniProt

    Q9NR56

    途径

    Ribonucleoprotein Complex Subunit Organization
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