SOGA2 抗体 (AA 884-1522)
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Quick Overview for SOGA2 抗体 (AA 884-1522) (ABIN7877038)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 884-1522
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原理
- MTCL1 Antibody / Microtubule cross-linking factor 1 / KIAA0802
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (K884-D1522) was used as the immunogen for the MTCL1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MTCL1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MTCL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SOGA2 (SOGA Family Member 2 (SOGA2))
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别名
- MTCL1
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背景
- MTCL1 (microtubule cross-linking factor 1), also known as CCDC165 (Coiledcoil domain-containing protein 165), SOGA2 or MTCL1, is a 1,905 amino acid protein that localizes to the cell membrane, cytoplasm and cytoskeleton. MTCL1 is a microtubule-associated factor that plays a role in regulating polarization and microtubule dynamics as well as the development and maintenance of non-centrosomal microtubule bundles. MTCL1 is encoded by a gene that maps to chromosome 18 and is expressed as four isoforms due to alternative splicing events. Chromosome 18 encodes over 300 genes and contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF? modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18.
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UniProt
- Q9Y4B5
抗原
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