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PC 抗体 (AA 88-1165)

The 兔 多克隆 anti-PC antibody is suitable to detect PC in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF, IHC (p) 和 FACS.
产品编号 ABIN7877025
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PC 抗体 (AA 88-1165) (ABIN7877025)

抗原

See all PC 抗体
PC (Pyruvate Carboxylase (PC))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PC antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

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    AA 88-1165

    原理

    Pyruvate Carboxylase Antibody / PC

    纯化方法

    Antigen affinity purified

    免疫原

    An E.coli-derived human recombinant protein (amino acids R88-D1165) was used as the immunogen for the Pyruvate Carboxylase antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Pyruvate Carboxylase antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Pyruvate Carboxylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    PC (Pyruvate Carboxylase (PC))

    别名

    Pyruvate Carboxylase

    背景

    This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

    UniProt

    P11498
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