PC 抗体 (AA 88-1165)
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Quick Overview for PC 抗体 (AA 88-1165) (ABIN7877025)
抗原
See all PC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 88-1165
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原理
- Pyruvate Carboxylase Antibody / PC
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids R88-D1165) was used as the immunogen for the Pyruvate Carboxylase antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Pyruvate Carboxylase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Pyruvate Carboxylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PC (Pyruvate Carboxylase (PC))
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别名
- Pyruvate Carboxylase
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背景
- This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
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UniProt
- P11498
抗原
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