ALDOB 抗体 (AA 85-364)
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Quick Overview for ALDOB 抗体 (AA 85-364) (ABIN7876985)
抗原
See all ALDOB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 85-364
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原理
- Aldolase B Antibody / ALDOB
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids Y85-Y364) was used as the immunogen for the Aldolase B antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Aldolase B antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Aldolase B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
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别名
- Aldolase B
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背景
- Aldolase B, also known as fructose-bisphosphate aldolase B or liver-type aldolase is one of three isoenzymes (A, B, and C) of the class I fructose 1,6-bisphosphate aldolase enzyme (EC 4.1.2.13), and plays a key role in both glycolysis and gluconeogenesis. It is mapped to 9q31.1. Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
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UniProt
- P05062
抗原
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