VWF 抗体 (AA 845-949)
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Quick Overview for VWF 抗体 (AA 845-949) (ABIN7876966)
抗原
See all VWF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 845-949
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原理
- von Willebrand Factor Antibody
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant human vWF fragment protein sequence (within amino acids 845-949) was used as the immunogen for the von Willebrand Factor antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the von Willebrand Factor antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the von Willebrand Factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- VWF (Von Willebrand Factor (VWF))
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别名
- von Willebrand Factor
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背景
- Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
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UniProt
- P04275
抗原
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