IRS2 抗体 (AA 83-1338)
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Quick Overview for IRS2 抗体 (AA 83-1338) (ABIN7876932)
抗原
See all IRS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 83-1338
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原理
- Insulin receptor substrate 2 Antibody / IRS2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids R83-E1338) was used as the immunogen for the Insulin receptor substrate 2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Insulin receptor substrate 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Insulin receptor substrate 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IRS2 (Insulin Receptor Substrate 2 (IRS2))
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别名
- Insulin receptor substrate 2
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背景
- Insulin receptor substrate 2 (IRS2) is a protein that in humans is encoded by the IRS2 gene. It is mapped to 13q34. This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. IRS2 is expressed in many cells, it may be essential for signaling by several receptor systems.
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UniProt
- Q9Y4H2
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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