PKD2 抗体 (AA 829-893)
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Quick Overview for PKD2 抗体 (AA 829-893) (ABIN7876929)
抗原
See all PKD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 829-893
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原理
- Polycystin 2 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids S829-R893) was used as the immunogen for the Polycystin 2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Polycystin 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Polycystin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
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别名
- Polycystin 2
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背景
- Polycystin-2 is a protein that in humans is encoded by the PKD2 gene. It is mapped to 4q22.1. This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
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UniProt
- Q13563
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途径
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
抗原
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