EIF3C 抗体 (AA 81-637)
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Quick Overview for EIF3C 抗体 (AA 81-637) (ABIN7876897)
抗原
See all EIF3C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-637
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原理
- EIF3C Antibody / Eukaryotic translation initiation factor 3 subunit C
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids E81-Q637) was used as the immunogen for the EIF3C antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the EIF3C antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the EIF3C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))
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别名
- EIF3C
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背景
- Eukaryotic translation initiation factor 3 subunit C (eIF3c) is a protein that in humans is encoded by the EIF3C gene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
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UniProt
- Q99613
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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