RASGRP1 抗体 (AA 8-678)
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Quick Overview for RASGRP1 抗体 (AA 8-678) (ABIN7876843)
抗原
See all RASGRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-678
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原理
- RASGRP1 Antibody / RAS guanyl-releasing protein 1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R8-Q678) was used as the immunogen for the RASGRP1 antibody.
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亚型
- IgG
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anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 598-797) antibody
RASGRP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 495-521) antibodyRASGRP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21940 unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) antibodyRASGRP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4630 unconjugated Recombinant Antibody
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 8-678) antibodyRASGRP1 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 594-716) antibodyRASGRP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 617-666) antibodyRASGRP1 适用: 人, 豚鼠, 小鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the RASGRP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RASGRP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
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别名
- RASGRP1
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背景
- RAS guanyl-releasing protein 1 is a protein that in humans is encoded by the RASGRP1 gene. This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).
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UniProt
- O95267
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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