GCKR 抗体 (AA 8-569)
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Quick Overview for GCKR 抗体 (AA 8-569) (ABIN7876839)
抗原
See all GCKR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-569
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原理
- Glucokinase Regulator Antibody / GCKR
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids Q8-Q569) was used as the immunogen for the Glucokinase Regulator antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Glucokinase Regulator antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Glucokinase Regulator antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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别名
- Glucokinase Regulator
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背景
- The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells). This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
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UniProt
- Q14397
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
抗原
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