FLCN 抗体 (AA 8-551)
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Quick Overview for FLCN 抗体 (AA 8-551) (ABIN7876838)
抗原
See all FLCN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-551
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原理
- Folliculin Antibody / FLCN
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids C8-K551) was used as the immunogen for the Folliculin antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Folliculin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Folliculin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FLCN (Folliculin (FLCN))
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别名
- Folliculin
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物质类
- Amino Acid
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背景
- Folliculin also known as FLCN, Birt-Hogg-Dube syndrome protein or FLCN_HUMAN is a protein that in humans is associated with Birt-Hogg-Dube syndrome and hereditary spontaneous pneumothorax. It is encoded by the Folliculin (FLCN) gene (alias BHD, FLCL) that acts as a tumor suppressor gene. It is mapped to 17p11.2. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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UniProt
- Q8NFG4
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途径
- Cell-Cell Junction Organization
抗原
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