SNX15 抗体 (AA 8-327)
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Quick Overview for SNX15 抗体 (AA 8-327) (ABIN7876821)
抗原
See all SNX15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-327
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原理
- Sorting nexin 15 Antibody / SNX15
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids D8-K327) was used as the immunogen for the Sorting nexin 15 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Sorting nexin 15 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Sorting nexin 15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SNX15 (Sorting Nexin 15 (SNX15))
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别名
- Sorting nexin 15
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背景
- Sorting nexin-15 is a protein that in humans is encoded by the SNX15 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
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UniProt
- Q9NRS6
抗原
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