Inhibin alpha 抗体 (AA 79-108)
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北京 101111
Quick Overview for Inhibin alpha 抗体 (AA 79-108) (ABIN7876794)
抗原
See all Inhibin alpha (INHA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 79-108
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原理
- Inhibin alpha Antibody / INHA
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 79-108 from the human protein was used as the immunogen for the Inhibin alpha antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Inhibin alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Inhibin alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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别名
- Inhibin alpha
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背景
- The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
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UniProt
- P05111
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途径
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
抗原
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