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Inhibin alpha 抗体 (AA 79-108)

The 兔 多克隆 anti-Inhibin alpha antibody is suitable to detect Inhibin alpha in samples from 人 和 小鼠. It has been validated for WB, IF, IHC (p) 和 FACS.
产品编号 ABIN7876794
发货至: 中国
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Quick Overview for Inhibin alpha 抗体 (AA 79-108) (ABIN7876794)

抗原

See all Inhibin alpha (INHA) 抗体
Inhibin alpha (INHA) (Inhibin, alpha (INHA))

适用

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人, 小鼠

宿主

  • 146
  • 46
  • 2

克隆类型

  • 118
  • 77
多克隆

标记

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This Inhibin alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

    • 21
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    • 1
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    • 1
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    AA 79-108

    原理

    Inhibin alpha Antibody / INHA

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 79-108 from the human protein was used as the immunogen for the Inhibin alpha antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the Inhibin alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Inhibin alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Inhibin alpha (INHA) (Inhibin, alpha (INHA))

    别名

    Inhibin alpha

    背景

    The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

    UniProt

    P05111

    途径

    Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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