TRIM24 抗体 (AA 789-843)
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Quick Overview for TRIM24 抗体 (AA 789-843) (ABIN7876792)
抗原
See all TRIM24 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 789-843
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原理
- Trim24 Antibody / Tif1 alpha / Tif1a
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 789-843 from the mouse protein was used as the immunogen for the Trim24 antibody.
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亚型
- Ig Fraction
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anti-Tripartite Motif Containing 24 (TRIM24) (AA 432-569) antibody
TRIM24 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 2F2 unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (AA 700-750) antibodyTRIM24 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) antibodyKD Validated TRIM24 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB4235 unconjugated Recombinant Antibody
anti-Tripartite Motif Containing 24 (TRIM24) (AA 706-964) antibodyTRIM24 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal 4G6C2 unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (AA 789-843), (C-Term) antibodyTRIM24 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB51160 unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (C-Term) antibodyTRIM24 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (C-Term) antibodyTRIM24 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (C-Term) antibodyTRIM24 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) antibodyTRIM24 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 24 (TRIM24) (AA 700-750) antibodyTRIM24 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Trim24 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Trim24 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
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别名
- Trim24
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背景
- Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac) (By similarity). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis via its effects on p53/TP53 levels. Up-regulates ligand- dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, such as RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes. Required for normal transition from proliferating neonatal hepatocytes to quiescent adult hepatocytes.
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UniProt
- Q64127
抗原
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