PIK3AP1 抗体 (AA 78-583)
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Quick Overview for PIK3AP1 抗体 (AA 78-583) (ABIN7876786)
抗原
See all PIK3AP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 78-583
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原理
- PIK3AP1 Antibody
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids H78-R583) was used as the immunogen for the PIK3AP1 antibody.
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亚型
- IgG
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anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) antibody
PIK3AP1 适用: 人, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 7G9 unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) antibodyPIK3AP1 适用: 人, 大鼠, 猴 WB, FACS 宿主: 小鼠 Monoclonal 6H6 unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 489-730) antibodyPIK3AP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 397-650) antibodyPIK3AP1 适用: 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 601-700) antibodyPIK3AP1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C2 unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 293-404) antibodyPIK3AP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 639-668), (C-Term) antibodyPIK3AP1 适用: 人 WB 宿主: 兔 Polyclonal RB32640 unconjugated
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应用备注
- Optimal dilution of the PIK3AP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PIK3AP1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))
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别名
- PIK3AP1
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背景
- Phosphoinositide 3-kinase adapter protein 1 is an enzyme that in humans is encoded by the PIK3AP1 gene. BCAP (B cell adaptor for phosphoinositide 3-kinase (PI3K)), also known as PI3KAP1, participates in linking the B cell antigen receptor (BCR) with the PI3K pathway. Tyrosine phosphorylation of BCAP by BCR-associated protein tyrosine kinases, such as Syk and Btk, generates binding sites for the p85 subunit of PI3K, resulting in activation of the PI3K pathway. Human and mouse BCAP contain 3 YXXM SH2 binding motifs for interaction with PI3K. BCAP null mice have deficient immune function, with B cells that exhibit enhanced apoptosis.
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UniProt
- Q6ZUJ8
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途径
- Activation of Innate immune Response, BCR Signaling, Warburg Effect
抗原
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