Hexokinase 抗体 (AA 78-108)
The 兔 多克隆 anti-Hexokinase antibody is suitable to detect Hexokinase in samples from 人 和 大鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN7876776
发货至:
中国
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Quick Overview for Hexokinase 抗体 (AA 78-108) (ABIN7876776)
抗原
See all Hexokinase 抗体
Hexokinase
适用
人, 大鼠
宿主
兔
克隆类型
多克隆
标记
This Hexokinase antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 78-108
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原理
- Hexokinase Antibody / HK1
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 78-108 from the human protein was used as the immunogen for the Hexokinase antibody.
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亚型
- Ig Fraction
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anti-Hexokinase (AA 1-917) antibody
适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D7 unconjugated
anti-Hexokinase (AA 1-917) antibody适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 4D7 unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Hexokinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Hexokinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Hexokinase
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背景
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. The hexokinase gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of the hexokinase gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. HK1 encodes the ubiquitously expressed isoform. Its 5' end includes an exon which is unique to this transcript and which encodes a distinct N-terminus that contains the porin binding domain (PBD). The porin binding domain mediates association with the mitochondrial membrane.
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UniProt
- P19367
抗原
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