Ancient Ubiquitous Protein 1 抗体 (AA 77-399)
Our Local Distributor
北京 101111
Quick Overview for Ancient Ubiquitous Protein 1 抗体 (AA 77-399) (ABIN7876763)
抗原
See all Ancient Ubiquitous Protein 1 (Aup1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 77-399
-
原理
- Ancient ubiquitous protein 1 Antibody / AUP1
-
纯化方法
- Antigen affinity purified
-
免疫原
- Recombinant human protein (amino acids A77-R399) was used as the immunogen for the Ancient ubiquitous protein 1 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Ancient ubiquitous protein 1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Ancient ubiquitous protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Ancient Ubiquitous Protein 1 (Aup1)
-
别名
- Ancient ubiquitous protein 1
-
背景
- Ancient ubiquitous protein 1 is a protein that in humans is encoded by the AUP1 gene. The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.
-
UniProt
- Q9Y679
抗原
-