Neurexin 1 抗体 (AA 77-110)
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北京 101111
Quick Overview for Neurexin 1 抗体 (AA 77-110) (ABIN7876757)
抗原
See all Neurexin 1 (NRXN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 77-110
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原理
- NRXN1 Antibody / Neurexin 1 beta
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 77-110 from the human protein was used as the immunogen for this NRXN1 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the NRXN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4oC for up to one month. For long term, aliquot the NRXN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Neurexin 1 (NRXN1)
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别名
- NRXN1
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背景
- Neurexin 1 is primarily known for its role in the formation and maintenance of synapses, the connections between neurons that allow for communication in the brain. It acts as a cell adhesion molecule, helping to guide the development of synapses and ensuring proper signaling between neurons. Studies have shown that mutations in the NRXN1 gene can lead to disruptions in synaptic function, ultimately impacting brain development and function. These mutations have been associated with a variety of neurological disorders, including autism spectrum disorder, schizophrenia, and intellectual disabilities.
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UniProt
- P58400
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途径
- Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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