NDE1 抗体 (AA 74-335)
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Quick Overview for NDE1 抗体 (AA 74-335) (ABIN7876714)
抗原
See all NDE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 74-335
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原理
- NDE1 Antibody / NudE
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids E74-C335) was used as the immunogen for the NDE1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NDE1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NDE1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NDE1
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别名
- NDE1
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背景
- Nuclear distribution protein nudE homolog 1 is a protein that in humans is encoded by the NDE1 gene. This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants.
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UniProt
- Q9NXR1
抗原
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