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CD207 抗体 (AA 74-213)

This 小鼠 单克隆 antibody specifically detects CD207 in WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7876709
发货至: 中国
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Quick Overview for CD207 抗体 (AA 74-213) (ABIN7876709)

抗原

See all CD207 抗体
CD207 (CD207 Molecule, Langerin (CD207))

适用

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  • 56
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  • 2
  • 2
  • 1
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宿主

  • 74
  • 64
  • 16
小鼠

克隆类型

  • 100
  • 54
单克隆

标记

  • 70
  • 9
  • 8
  • 6
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
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  • 2
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  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
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  • 1
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  • 1
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  • 1
  • 1
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This CD207 antibody is un-conjugated

应用范围

  • 38
  • 31
  • 29
  • 14
  • 7
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

LGRN-1821
  • 抗原表位

    • 39
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    AA 74-213

    原理

    Langerin Antibody / CD207

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 74-213) was used as the immunogen for the Langerin antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the Langerin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Langerin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    CD207 (CD207 Molecule, Langerin (CD207))

    别名

    Langerin

    背景

    Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

    UniProt

    Q9UJ71
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