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CD207 抗体 (AA 74-213)

The 小鼠 单克隆 anti-CD207 antibody (Clone LGRN-1821) (ABIN7876708) specifically detects CD207 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7876708
发货至: 中国
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Quick Overview for CD207 抗体 (AA 74-213) (ABIN7876708)

抗原

See all CD207 抗体
CD207 (CD207 Molecule, Langerin (CD207))

适用

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宿主

  • 74
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  • 16
小鼠

克隆类型

  • 100
  • 54
单克隆

标记

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This CD207 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

质量等级

Carrier-free

克隆位点

LGRN-1821
  • 抗原表位

    • 39
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    AA 74-213

    原理

    Langerin Antibody / CD207 (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 74-213) was used as the immunogen for the Langerin antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the Langerin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Langerin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    CD207 (CD207 Molecule, Langerin (CD207))

    别名

    Langerin

    背景

    Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

    UniProt

    Q9UJ71
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