Recombinant CD207 抗体 (AA 74-213)
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北京 101111
Quick Overview for Recombinant CD207 抗体 (AA 74-213) (ABIN7876705)
抗原
See all CD207 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 74-213
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原理
- Recombinant Langerin Antibody / CD207
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 74-213 was used as the immunogen for the recombinant Langerin antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the recombinant Langerin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant Langerin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD207 (CD207 Molecule, Langerin (CD207))
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别名
- Langerin
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背景
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
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UniProt
- Q9UJ71
抗原
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