RBP4 抗体 (AA 74-182)
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Quick Overview for RBP4 抗体 (AA 74-182) (ABIN7876702)
抗原
See all RBP4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 74-182
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原理
- RBP Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Retinol binding protein purified from human plasma was used as the immunogen for this RBP antibody. Its epitope localizes between amino acids 74-182 of human RBP.
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亚型
- IgG1, kappa
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anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 63-245) antibody
RBP4 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) antibodyRBP4 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 18-201) antibodyRBP4 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-202) antibodyRBP4 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4H7 unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) antibodyRBP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinol Binding Protein 4, Plasma (RBP4) (AA 19-202) antibodyRBP4 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D9 unconjugated
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应用备注
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The optimal dilution of the RBP antibody for each application should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the RBP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
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别名
- RBP
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背景
- Recognizes a protein of 21 kDa-25 kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This MAb recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.
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UniProt
- P02753
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途径
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
抗原
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