MAEL 抗体 (AA 73-347)
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Quick Overview for MAEL 抗体 (AA 73-347) (ABIN7876680)
抗原
See all MAEL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 73-347
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原理
- MAEL Antibody / Maelstrom homolog
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (E73-Q347) was used as the immunogen for the MAEL antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MAEL antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MAEL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))
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别名
- MAEL
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背景
- The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
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UniProt
- Q96JY0
抗原
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