SAP130 抗体 (AA 728-1181)
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Quick Overview for SAP130 抗体 (AA 728-1181) (ABIN7876645)
抗原
See all SAP130 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 728-1181
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原理
- SAP130 Antibody / SF3B3
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R728-Q1181) was used as the immunogen for the SAP130 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SAP130 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SAP130 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SAP130 (Sin3A-Associated Protein, 130kDa (SAP130))
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别名
- SAP130
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背景
- Splicing factor 3B subunit 3 is a protein that in humans is encoded by the SF3B3 gene. This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
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UniProt
- Q15393
抗原
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