TTR 抗体 (AA 71-98)
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北京 101111
Quick Overview for TTR 抗体 (AA 71-98) (ABIN7876613)
抗原
See all TTR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 71-98
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原理
- Transthyretin Antibody / TTR / Prealbumin
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 71-98 from the human protein was used as the immunogen for the Transthyretin antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Transthyretin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Transthyretin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TTR (Transthyretin (TTR))
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别名
- Transthyretin
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背景
- Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
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UniProt
- P02766
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途径
- Hormone Transport
抗原
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