OTC 抗体 (AA 71-98)
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Quick Overview for OTC 抗体 (AA 71-98) (ABIN7876612)
抗原
See all OTC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 71-98
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原理
- Ornithine transcarbamylase Antibody / OTCase / OTC
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 71-98 from the human protein was used as the immunogen for the Ornithine transcarbamylase antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Ornithine transcarbamylase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Ornithine transcarbamylase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- OTC (Ornithine Carbamoyltransferase (OTC))
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别名
- Ornithine transcarbamylase
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背景
- Ornithine transcarbamylase is an enzyme that is responsible for catalyzing the reaction between ornithine and carbamoyl phosphate, ultimately forming citrulline. Citrulline then goes on to participate in the urea cycle, where it helps convert toxic ammonia into urea, which can be safely excreted by the body. A deficiency in this enzyme can lead to a rare genetic disorder known as ornithine transcarbamylase deficiency. Individuals with this condition are unable to properly metabolize ammonia, leading to a buildup of toxic levels in the blood. This can result in a range of symptoms, from mild to severe, including fatigue, seizures, and even coma if left untreated.
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UniProt
- P00480
抗原
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